The organic compound ramipril found in Altace question? - ramipril more drug_uses
I'm writing a report on ramipril and need to know the origin of these compounds. Is that a natural or man? What is the mood? I know that makes pharaceuticals Altace kings, but he said that the process of how the incident occurred. Does anyone know a good link for this information?
Saturday, December 12, 2009
Ramipril More Drug_uses The Organic Compound Ramipril Found In Altace Question?
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2 comments:
No product is not, of course, even if it is an amino acid derivative. The products are natural substances found in nature that have pharmacological activity.
The synthesis was described by Volker Teetz, and I provided the following:
Title: Synthesis of unnatural amino acids - (S, S, S)-2-bicyclo [3.3.0] octane-3 --
Carboxylic acids
Author: Teetz V, et al.
Posted: Tetrahedron Letters [0040-4039] Year: 1984 Vol: 25 ISS: 40 pg :4479-4482
Another good article that describes the complete synthesis of ramipril:
Title: Synthesis of highly active inhibitor of angiotensin angiotensin converting enzyme - 2 - [N-[(S)-1-ethoxycarbonyl-3 --
Phenyl]-L-alanyl] - (1S, 3S, 5S) -2 --
bicyclo [3.3.0] octane-3-carboxylic acid
Author: Teetz V, et al
Posted: drug research [0004-4172] Year: 1984 Vol :34-2 ISS: 10B PG: 1399 -1401
Both products are currently the best source. I also found a new synthesis, which was patented recently. Find here: http://www.wipo.int/pctdb/en / wo.jsp? r = 2 ...
Hope this helps.
Try:
http://en.wikipedia.org/wiki/Ramipril
http://www.medicinenet.com/ramipril/article.htm
http://www.rxlist.com/cgi/generic/ramipril.htm
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